A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue.
نویسندگان
چکیده
We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H(2)O(2) in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.
منابع مشابه
A two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue.
We report a two-photon fluorescent probe (PN1) that can be excited by 750 nm femto-second pulses, shows high photostability and negligible toxicity, and can visualize H(2)O(2) distribution in live cells and tissue by two-photon microscopy.
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عنوان ژورنال:
- Chemical communications
دوره 48 29 شماره
صفحات -
تاریخ انتشار 2012